Abstract: 

Identifying lethal sRNA genes: We established a novel screening strategy that integrates the use of an RNA expression system to search uncharacterized small RNAs and their antisense counterparts for lethal phenotype.

Authors: 

Mok WW, Navani NK, Barker C, Sawchyn BL, Gu J, Pathania R, Zhu RD, Brown ED, Li Y.

Reference:

Chembiochem. 2009 Jan 26;10(2):238-41. doi: 10.1002/cbic.200800591.